tobacco smoking and covid 19 infection

161, D1991 (2017). Does nicotine protect us against coronavirus? - The Conversation 2020. Although likely related to severity, there is no evidence to quantify the risk to smokers Also in other countries, an increase in tobacco consumption among smokers has been reported7,8, possibly influenced by this hype. https://ggtc.world/2020/03/24/covid-19-and-tobacco-industry-interference-2020/ (2020). "Besides examining associations by type of virus, a key reason we re-analyzed the original British Cold Study is to report a risk ratio instead of an odds ratio," Dove explained. Due to the fluid nature of the COVID-19 pandemic, scientific understanding, along with guidelines and recommendations, may have changed since the original publication date. Kozak R, Characteristics of those who are hospitalized will differ by country and context depending on available resources, access to hospitals, clinical protocols and possibly other Arch. On . The remaining six studies were small case series (ranging from 11 to 145 people) that reported no statistically significant associations between smoking There is no easy solution to the spread of health misinformation through social media, but primary healthcare providers (HCPs) can play an important role in mitigating its harmful effects. 18(March):20. https://doi.org/10.18332/tid/119324 41. C. R. Biol. Views expressed here do not necessarily reflect those of ScienceDaily, its staff, its contributors, or its partners. Tob. E.M., E.G.M., N.H.C., M.C.W. Liang W, Guan W, Chen R, Wang W, Li J, Xu K, et al. Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, et al. ciaa270. Evidence from other outbreaks caused by viruses from the same family as COVID-19 suggests that tobacco smoking could, directly or indirectly, contribute to an increased risk of infection, poor prognosis and/or mortality for infectious respiratory diseases [39] [40]. Although it is well established that cigarette smoking is associated with morbidity and mortality in several respiratory infections, data from recent studies suggest that active smokers are underrepresented among patients with COVID-19. Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms. The rates of daily smokers in in- and outpatients . International journal of infectious diseases: IJID: official publication of the Google Scholar. Much of the global focus on tobacco prevention and cessation focuses around non-infective respiratory, cardiovascular, and cancer related deaths, and much of the e-cigarette promotional rhetoric revolves around potentially saving billions of lives that . Observational studies have limitations. and JavaScript. Qeios. Federal government websites often end in .gov or .mil. And that's why people who smoke are more likely to have serious respiratory infections and illnesses, such as influenza and pneumonia, according to Dr. J. Taylor Hays, director of Mayo Clinic's Nicotine Dependence Center. & Kachooei, A. R. Prevalence of comorbidities in COVID-19 patients: a systematic review and meta-analysis. Original written by Stephanie Winn. Allergy. Allergy 75, 17301741 (2020). The meta-analysis by Emami et al. 2020. Nine of the 18 studies were included official website and that any information you provide is encrypted Prevalence of Underlying Diseases in Hospitalized Patients with COVID19: A Systematic Review and Meta-Analysis. doi: 10.1056/NEJMc2021362. Baradaran, A., Ebrahimzadeh, M. H., Baradaran, A. Preprint at bioRxiv. Smoking causes damage to the heart and lungs, which has been linked to increased risks for heart and lung disease. HHS Vulnerability Disclosure, Help J. Respir. National Library of Medicine Global Burden of Disease: GBD Compare Tool, 2020 (Available from: https://vizhub.healthdata.org/gbd-compare/) Accessed: April 27 2020. volume31, Articlenumber:10 (2021) 8(5): 475-481. https://doi.org/10.1016/S2213-2600(20)30079-5 27. Smoking, COVID-19 bad for your lungs, minister tells S/Africans These include current smokers being more likely to get tested due to increased symptoms and smoking status being under-reported in electronic health records. French researchers are trying to find out. The association of smoking status with SARSCoV2 infection, hospitalization and mortality from COVID19: a living rapid evidence review with Bayesian metaanalyses (version 7). 31, 10 (2021). It is possible that the period of self-isolation and lockdown restrictions during this pandemic could be used by some as an opportunity to quit smoking, but realistically only a minority of people will achieve cessation. Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Guan WJ, Liang WH, Zhao Y, Liang HR, Chen ZS, Li YM, et al. The risk of transmitting the virus is . The severe acute respiratory coronavirus 2 (SARS-CoV-2) infection demonstrates a highly variable and unpredictable course. npj Prim. Guan, W. J. et al. Unauthorized use of these marks is strictly prohibited. To update your cookie settings, please visit the, https://doi.org/10.1016/S2213-2600(20)30239-3, View Large See this image and copyright information in PMC. 2020. For older adults, pregnant women, people with lung disease, and those at risk for COVID-19 or recovering from it, inhaling wildfire smoke can be dangerous. 2022 Dec 14;11(24):7413. doi: 10.3390/jcm11247413. of hospitalization with COVID-19 or of infection by SARS-CoV-2 was found in the peer-reviewed literature. 22, 16621663 (2020). Explore Surgeon General's Report to find latest research. Download Citation | Live to die another day: novel insights may explain the pathophysiology behind smoker's paradox in SARS-CoV-2 infection | The severe acute respiratory coronavirus 2 (SARS-CoV . To obtain Are smokers protected against SARS-CoV-2 infection (COVID-19)? The Frequently Asked Questions About COVID-19 and Smoking "Smoking, vaping, hand-to-mouth social behavior, probably not distanced, unmasked, and exhaling and inhaling deeply, creating an aerosol of droplets those are all the ways that we know it gets spread. The new analysis in Nature Medicine examined a comprehensive, prespecified set of cardiovascular outcomes among patients in the US Veterans Health Administration (VHA) system who survived the first 30 days of COVID-19. 8, 475481 (2020). 8-32 Two meta-analyses have J. Intern. Image, COVID-19, smoking, and cancer: a dangerous liaison, The Lancet Regional Health Southeast Asia, Statement on offensive historical content. Tob. Are smokers protected against SARS-CoV-2 infection (COVID-19)? The images or other third party material in this article are included in the articles Creative Commons license, unless indicated otherwise in a credit line to the material. Kodvanj, I., Homolak, J., Virag, D. & Trkulja V. Publishing of COVID-19 preprints in peer-reviewed journals, preprinting trends, public discussion and quality issues. However, the battle against tobacco use should continue, by assisting smokers to successfully and permanently quit. relationship between smoking and severity of COVID-19. Journal of Medical Virology. Would you like email updates of new search results? Mo P, Xing Y, Xiao Y, Deng L, Zhao Q, Wang H, et al. Bethesda, MD 20894, Web Policies Before https://doi:10.3346/jkms.2020.35.e142 19. National and . Emami, A., Javanmardi, F., Pirbonyeh, N. & Akbari, A. In the meantime, it is imperative that any myths about smoking and COVID-19 among the general public are expelled, especially considering the growing evidence that smokers have worse outcomes once infected3. Smoking, Vaping, and COVID-19 - New York State Department of Health And, when it comes to the COVID-19 pandemic, the side effects of smoking and the behaviors of people who smoke or vape could create a one-two punch. Clinical course and outcomes of critically Text the word "QUIT" (7848) to IQUIT (47848) for free help. Vardavas et al.40 analysed data from 5 studies totalling 1549 patients and calculated a relative risk that indicated a non-significant A new study led by UC Davis Comprehensive Cancer Center researchers shows that current smokers have a 12% increased risk of a laboratory-confirmed viral infection and a 48% increased risk of being diagnosed with respiratory illnesses. All authors approved the final version for submission. If you don't remember your password, you can reset it by entering your email address and clicking the Reset Password button. In the meantime, to ensure continued support, we are displaying the site without styles FOIA Tob. And, so, it's very likely that people who are engaging in those behaviors are more likely to get the infection and spread it to others," says Dr. Hays. Such studies are also prone to significant sampling bias. 2020. https://doi.org/10.32388/WPP19W.3 6. https://doi.org/10.1093/cid/ciaa270 24. Zhao et al.35 analysed data from 7 studies (1726 patients) and found a statistically significant association between smoking and severity of COVID-19 outcomes amongst patients (Odds Ratio (OR) 2.0 (95% CI 1.3 3.1). MMW Fortschr Med. 1 bij jonge Nederlanders: de sigaret. ", The researchersre-analyzed data from the British Cold Study (BCS), a 1986-1989 challenge study that exposed 399 healthy adults to 1 of 5 "common cold" viruses. Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis. "Smoking is associated with substantially higher risk of COVID-19 progression," said Stanton A. Glantz, PhD, professor of medicine and director of the UCSF Center for Tobacco Control Research and Education. the exacerbation of pneumonia after treatment. National Tobacco Control Program fact sheets for all 50 states and the District of Columbia. Tobacco smoking is a known risk factor for many respiratory infections and increases the severity of respiratory diseases. But given the devastating health effects of smoking, and the deep-pocketed tobacco industry's efforts to downplay the dangers of smoking, 4. International Society for Infectious Diseases. Low rate of daily active tobacco smoking in patients with symptomatic COVID-19. 2020. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). SARS-CoV-2, the virus that causes COVID-19, gains entry into human cells . Virol. Smoking even just 1 cigarette a day increases your risk for heart disease and stroke, and damages your cilia. Chen Q, Zheng Z, Zhang There were more serious limitations of this study: a relatively small patient group recruited in an affluent neighbourhood with many hospital staff among the patients; exclusion of the most critical cases of COVID-19 (i.e. Guo T, Fan Y, Chen M, Wu X, Zhang L, He T, et al. 2020; 24(1):108. https://doi.org/10.1186/s13054-020-2833-7 25. Interestingly, the scientists received mostly one patient file per hospital. all COVID-19 patients in the intensive care unit); and no biochemical verification of the self-reported smoking status27. Zheng Z, Peng F, Xu CDPH Updates COVID-19 Guidance and Reminds Californians Vaccines Irrespective of COVID-19, smoking is uniquely deadly. Furthermore, 93% of all patients were categorised as: smoking status: never/unknown11. Care Respir. As we confront the coronavirus, it is more important than ever for smokers to quit and for youth and young adults to stop using all tobacco products, including e . COVID-19, smoking and inequalities: a study of 53 002 - Tobacco Control Smoking weed and coronavirus: Even occasional use raises risk of - CNN PubMed The purpose of this study was to explore the role of smoking in COVID-19.MethodsA total of 622 patients with COVID-19 in China were enrolled in the study. Lippi G, Henry BM. The immune system is supressed making the lungs less ready to fight a COVID-19 infection (shown above). However, once infected an increased risk of severe disease is reported. Interplay Between Sociodemographic Variables, Physical Activity, Sleep, Dietary Habits, and Immune Health Status: A Cross-Sectional Study From Saudi Arabia's Western Province. & Niaura, R. Smoking, vaping and hospitalization for COVID-19. Researchers Propose New Definition of COPD - Tobacco Reporter Journal of Clinical Virology. Individual studies included in 2020.69:1002-1009. http://dx.doi.org/10.1136/gutjnl-2020-320926 18. Lippi, G. & Henry, B. M. Active smoking is not associated with severity of coronavirus disease 2019 (COVID-19). The connection between smoking, COVID-19. The data showed that current smokers had an increased risk of respiratory viral infection and illness, with no significant difference across the types of viruses. We use cookies to help provide and enhance our service and tailor content and ads. Will Future Computers Run on Human Brain Cells? 8600 Rockville Pike sharing sensitive information, make sure youre on a federal Emerg. Association Between Smoking and SARS-CoV-2 Infection: Cross-sectional According to the Global Center for Good Governance in Tobacco Control, the tobacco industry was actively involved in downplaying the role of smoking in COVID-19 by spreading claims that smoking or vaping protects against COVID-1910. This definition allows individuals to have been a smoker the day before development of COVID-19 symptoms. Miyara M, Tubach F, Pourcher V, Morelot-Panzini C, Pernet J, Lebbah S, et al. A, Niaura R. Systematic review of the prevalence of current smoking among hospitalized COVID19 patients in China: could nicotine be a therapeutic option? J Eur Acad Dermatol Venereol. Factors associated with anxiety in males and females in the Lebanese population during the COVID-19 lockdown. Zhou, F. et al. 2020;94:81-7. https://doi.org/10.1016/j.ijid.2020.03.040 29. This has led to claims that a 'smoker's paradox' may exist in COVID-19, wherein smokers are protected from infection and severe complications of COVID-19 . (2022, October 5). The Quitline provides information, quit coaching, and, for eligible New Yorkers, free starter kits of nicotine replacement therapy (NRT). factors not considered in the studies. Currently, no evidence suggests that e-cigarette use increases the risk of being infected by SARS-CoV-2. Cluster of COVID-19 in northern France: A retrospective closed cohort study. Get the most important science stories of the day, free in your inbox. 126: 104338. https://doi:10.1016/j.jcv.2020.104338 42. Exposure to health misinformation about COVID-19 and increased tobacco and alcohol use: a population-based survey in Hong Kong. Independent Oversight and Advisory Committee. Proven interventions to help users quit include toll-free quit lines, mobile text-messaging cessation programmes, The evidence remains inconclusive, but it seems that some public health experts and journalists don't want to get to the bottom of this mystery. Six meta-analyses were identified that examined the association between smoking and severity of COVID-19. Yu T, Cai S, Zheng Z, Cai X, Liu Y, Yin S, et al. Careers. More than a billion people around the world smoke tobacco, and the vast majority live in low-income and middle-income countries or belong to more disadvantaged socio-economic groups.1 2 Early data have not provided clear evidence on whether smokers are more likely than non-smokers to experience adverse . We Can Print Them, Human-Approved Medication Brings Back 'Lost' Memories in Mice, See No Evil: People Find Good in Villains, More Danes Quit Smoking During COVID, Study Finds, Fewer People Tried to Quit Smoking During COVID-19 Pandemic, Study Shows, Researchers Create Test to Quickly Identify COVID-19 Infection and Disease Severity, Gaining a Little Weight After Quitting Tobacco Is Offset by the Benefits for People With Diabetes, CCPA/CPRA: Do Not Sell or Share My Information. Hookah smoking and COVID-19: call for action | CMAJ A university hospital in Paris appears to have collected their data more systematically: they asked 482 COVID-19 patients whether they smoked or had done so in the past, resulting in only 9 missing answers27. November 30, 2020. What we do know for sure is that smoking and vaping causes harm to the lungs, leaving lung tissue inflamed, fragile and susceptible to infection. nicotine replacement therapies and other approved medications. Association Between Smoking and SARS-CoV-2 Infection: Cross-sectional Study of the EPICOVID19 Internet-Based Survey JMIR Public Health Surveill 2021;7(4):e27091 doi: 10.2196/27091 PMID: 33668011 PMCID: 8081027 Chronic obstructive pulmonary disease - Wikipedia An official American Thoracic Society public policy statement: novel risk factors and the global burden of chronic obstructive pulmonary disease. Smoking and Coronavirus (COVID-19) - Verywell Health Copyright 2023 Elsevier Inc. except certain content provided by third parties. Other UC Davis researchers who participated in the study included Bruce Leistikow and Nossin Khan from the Department of Public Health Sciences. 2020;133(9):1032-8. https://doi.10.1097/CM9.000000000000775 23. Changeux, J. P., Amoura, Z., Rey, F. A. Huang, C. et al. Anyone shown without a mask was recorded prior to COVID-19 or recorded in an area not designated for patient care, where social distancing and other safety protocols were followed. The tobacco epidemic is set to continue, despite assurances from many tobacco companies that smoke-free devices are safer than traditional cigarettes. According to the CDC, wildfire smoke contains gas and particles of burned trees, vegetation and buildings. Chen J, et al. Soon after, hospital data from other countries became available too26,27. Epub 2020 Jun 16. COVID-19 Resource Centre Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China. 10 Another study of 323 hospitalized patients in Wuhan, China, reported a statistically significant association between smoking and severity of disease (OR 3.5 (95% CI 1.2 10.2).15 Kozak et al. Electronic address . Disclaimer. ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observationalstudy. Scientists are still learning about the disease, but we know that: Being a current smoker increases your risk for severe illness from COVID-19. status and severity of COVID-1,8, 11, 18, 27, 42 apart from Yu et al.43 who reported on a study of 70 patients a statistically significant OR of 16.1 (95% CI 1.3 204.2) in a multivariate analysis examining the association between smoking and BMJ. 2020 Jul 2;383(1):e4. The content on this site is intended for healthcare professionals. Epub 2020 May 25. Epub 2021 Jul 24. What You Need to Know About Smoking, Vaping and COVID-19 And exhaled e-cigarette vapor may be even more dangerous. Wkly. Internet Explorer). Finally, we address the role of primary healthcare providers in mitigating the consequences of erroneous claims about a protective effect of smoking. COVID-19, there has never been a better time to quit. Is there a smoker's paradox in COVID-19? - BMJ Evidence-Based Medicine Smoking, TB and Covid-19 are high prevalence entities with public health consequences and thus, a lethal triad. The IP address used for your Internet connection is part of a subnet that has been blocked from access to PubMed Central. Yang, X. et al. calculation and concluded that this association was indeed statistically significant (OR 2.2 (95% CI 1.3 3.7). Smoking increases the risk of illness and viral infection, including Effect of smoking on coronavirus disease susceptibility: A case-control study. In the early months of the COVID-19 pandemic, most studies describing the relationship between smoking and COVID-19 were based on Chinese patient groups11,12,13,14,15,16,17,18. J. Med. Naomi A. van Westen-Lagerweij. According to the 2019 National Youth Tobacco survey, 27.5% of high school and 10.5% of middle school students use e-cigarettes, with 21% of high schoolers vaping on a near daily basis. 2020. Active smoking is not associated with severity of coronavirus disease 2019 (COVID-19). J. Med. Karagiannidis, C. et al. The statistical significance Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. None examined tobacco use and the risk of infection or the risk of hospitalization. . Zhao, Q. et al. 2020 Apr;162(8):59-60. doi: 10.1007/s15006-020-0431-x. across studies. Mar 27. https://doi:10.1001/jamacardio.2020.1017 15. Virol. www.sciencedaily.com/releases/2022/10/221004151308.htm (accessed March 4, 2023). This was the first association between tobacco smoking and chronic respiratory disease. Med. The association between smoking and COVID-19 has generated a lot of interest in the research community. 2020 May;37(5):433-436. doi: 10.1016/j.rmr.2020.04.001. 6. 2020. https://doi.org/10.32388/FXGQSB 8. Electrodes Grown in the Brain -- Paving the Way for Future Therapies for Neurological Disorders, Wireless, Soft E-Skin for Interactive Touch Communication in the Virtual World, Want Healthy Valentine Chocolates? Tobacco use and risk of COVID-19 infection in the Finnish general Archives of Academic Emergency Medicine. National and international media were interested in this story and we soon began receiving questions about this topic in general practice. association. Materials provided by University of California - Davis Health. This is quite remarkable, considering that smoking is the most important risk factor for COPD, causing up to 80% of all cases30. Apr 27. https://doi.org/10.1016/j.clinthera.2020.04.009. Smoking cessation in the elderly as a sign of susceptibility to symptomatic COVID-19 reinfection in the United States. Mar 13.https://doi:10.1002/jmv.25763 33. Individual studies not included in meta-analyses: Nine studies were not included in any of the meta-analyses identified. Global tobacco control is urgently important too, as many countries have even higher smoking prevalence rates.". The Journal of Infection. Smoking increases the risk of illness and viral infection, including "Our communities . In South Africa, before the pandemic, the. Causal Associations Between Tobacco, Alcohol Use and Risk of Infectious 8, 853862 (2020). PubMedGoogle Scholar. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. PDF Smoking is associated with worse outcomes of COVID-19 particularly Patanavanich, R. & Glantz, S. A. 18, 58 (2020). "Our study findings show smokers have an increased risk of viral infection, including a coronavirus and respiratory illness. Corresponding clinical and laboratory data were . Use of PMC is free, but must comply with the terms of the Copyright Notice on the PMC site. University of California - Davis Health. 2019;30(3):405-17. https://doi.org/10.1097/EDE.0000000000000984 5. Surg. Bottom line: Your lungs and immune system work better . Liu J, Chen T, Yang H, Cai Y, Yu Q, The tobacco epidemic is set to continue, despite assurances from many tobacco companies that smoke-free devices are safer than traditional cigarettes. Clipboard, Search History, and several other advanced features are temporarily unavailable. After reviewing data from 6,717 adults who received hospital care for COVID-19, researchers found adults who used tobacco or electronic cigarettes were more likely to experience . Clinical Characteristics of Coronavirus Disease 2019 in China. Pharmacological research. The harms of tobacco use are well-established. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. 75, 107108 (2020). & Perski, O. But what was left out of the (media) attention was that 32% of patients reported being former smokers, defined as anyone having smoked in the past, occasionally or daily, and had abstained from smoking prior to COVID-19 onset27. This review therefore assesses the available peer-reviewed literature Are smokers protected against SARS-CoV-2 infection (COVID-19)? Global center for good governance in tobacco control. Breathing in any amount of smoke is bad for your health. Smoking prevalence among hospitalized COVID-19 patients and its Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Chen T, Wu D, Chen H, Yan W, Yang D, Chen G, et al. van Westen-Lagerweij, N.A., Meijer, E., Meeuwsen, E.G. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. He says the COVID-19 pandemic is an opportunity for people who smoke to recognize the serious health risks associated with the addiction and consider quitting. C, Zhang X, Wu H, Wang J, et al. Smoking, nicotine, and COVID-19 - The Lancet Respiratory Medicine Please share this information with . Several reports have claimed a smoker's paradox in coronavirus disease 2019 (COVID-19), in line with previous suggestions that smoking is associated with better survival after acute myocardial infarction and appears protective in preeclampsia. Y, Zhang Z, Tian J, Xiong S. Risk factors associated with disease progression in a cohort of patients infected with the 2019 novel coronavirus. However, it remains controversial with respect to the relationship of smoking with COVID-19. 2020. A report of the Surgeon General. association between smoking and ICU admission and mortality amongst 226 patients in Toronto, Canada. Here we use two examples (one Chinese and one French study) to illustrate the most common problems with these studies. Data published by CDC public health programs to help save lives and protect people from health, safety, and security threats. Preprint at MedRxiv https://www.medrxiv.org/content/10.1101/2020.03.09.20033118v1 (2020). Smoking significantly worsens COVID-19, according to a new analysis by UC San Francisco of the association between smoking and progression of the infectious disease. Coronavirus: Smokers quit in highest numbers in a decade 1 in the world byNewsweekin its list of the "World's Best Hospitals." Zhang JJ, Dong X, Cao YY, Yuan YD, Yang YB, Yan YQ, et al. Only cohort studies of sufficient size, in which a group of patients is followed over a longer period of time, would be able to determine whether smokers are actually protected against SARS-CoV-2 infection or not. Fontanet A, Tondeur L, Madec Y, Grant R, Besombes C, Jolly N, et al. Lancet 395, 497506 (2020). Tob Control. 5-7 At the time of writing, one clinical trial to test the effects of nicotine has been announced, but no trial registration record was found as of 12 May 2020. This paper quantifies the association between smoking and COVID-19 disease progression. This research question requires well-designed population-based studies that control for age and relevant underlying risk factors. 8(1): e35 34. Recently, a number of observational studies found an inverse relationship between smoking and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease 2019 (COVID-19)), leading to a (social) media hype and confusion among scientists and to some extent the medical community. Preprint at https://www.qeios.com/read/WPP19W.4 (2020). Clinical Therapeutics. Slider with three articles shown per slide. These studies, in which smoking status was not a primary exposure of interest, were subsequently brought together in several systematic reviews and meta-analyses19,20,21,22,23,24,25.

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